Fusa Tatsumi was born in Yao City, Osaka Prefecture, Japan on 25 April 1907. She was the fifth of six siblings. After graduating from elementary school, she practiced tea ceremony, flower arrangement, Okoto (a classical Japanese musical instrument), and obtained a diploma. At the age of 32, she married Ryutaro Tatsumi (巽龍太郎) and they moved to Kashiwara City, Osaka Prefecture. She gave birth to her eldest daughter in 1941 and her eldest son in 1947.
Tatsumi worked in a family orchard (growing peaches, plums, and grapes) until her husband died when she was about 55 years old. She would carry a basket of fruits harvested in her orchard on her back. Her family has attributed her longevity to this physical work.
As a hobby, Tatsumi enjoyed growing chrysanthemum flowers. However, when she was in her 70s, she fell after getting her clothes caught in her flowerbed, resulting in a broken femur. She still has the bolt in her leg. Other than her injury at that time, she has never been seriously ill or injured.
Tatsumi lived at home with her family until just before she was 107. She currently lives in a nursing home in Kashiwara, Osaka, Japan. In April 2017, she celebrated her 110th birthday with a small celebration.