Brígida Ruiz de Cuevas was a Paraguayan supercentenarian whose age has been validated by the Latin American Supercentenarians (LAS). At the time of death, she was the oldest (known) living person in Paraguay.

Casilda Ramona Benegas de Gallego was a Paraguayan-Argentinian supercentenarian whose age is validated by the Gerontology Research Group (GRG). She is the first validated supercentenarian born in Paraguay and is also the oldest validated person to ever die in Argentina. She was the oldest validated living person in Latin America from the death of Antonia da Santa Cruz on 23 January 2022 to her death five months later.