Tranquilina Urrutia Roque was born in Oaxaca, Mexico, on 6 July 1912. She had at least two daughters, Irena and Petra.
At the age of 108, she received the COVID-19 vaccine, making her one of the oldest known people in Mexico to receive the vaccine.
Tranquilina Urrutia Roque currently lives in Valerio Trujano, Oaxaca, Mexico.
On 7 July 2022, her age was validated by the Latin American Supercentenarians (LAS), one day after her 110th birthday. She became the first validated supercentenarian from the State of Oaxaca.