Guillon was born in Lyon, Auvergne-Rhône-Alpes, France, on 4 November 1910.
On her 100th birthday in November 2010, she was visited by the mayor of Verrières-le-Buisson, Bernard Mantienne, and his town councillors, Marie-Josiane Degerit and Fernand Biolley.
Guillon passed away in Verrières-le-Buisson, Essonne, Île-de-France, on 1 July 2021, at the age of 110 years, 209 days.
Her age has been validated by the European Supercentenarian Organisation (ESO), but is yet to be recognized by LongeviQuest.
* “Centenaire” – Mensuel de Verrières-le-Buisson (n°117), January 2011 (page 5)
* “Sr Francine Guillon a 108 ans” – Missionary Sisters of Our Lady of Africa, 5 January 2019