Hendrikje van Andel-Schipper was born as Hendrikje Schipper in the small village of Kloosterveen (by now part of Assen, The Netherlands) on 29 June 1890 to parents Marines Schipper and Eberta Venekamp. Born several months too early, she had fragile health during her youth. She only survived birth after her grandmother insisted on taking care of her. Also, it was advised that she would not attend school due to often being sick in her childhood. As a result, she was homeschooled by her parents, but would later end up in front of class as a teacher, when she started teaching.

In 1925, at the age of 35, Van Andel-Schipper moved to The Hague together with her parents, where she would meet her future husband Dick van Andel, who worked at the tax office of Amsterdam, ten years later. As he had been married before, Van Andel-Schipper’s parents did not approve of the relationship, prompting her to break ties with them. Because of the low amount of food in multiple Dutch cities during World War II, Mrs. Van Andel-Schipper had no choice but to sell her jewelry to buy some food. She would be married to her husband for about twenty years, until his death from cancer in 1960; consequently, Hendrikje moved back to Hoogeveen, Drenthe. She remained in good health for about thirty years, before she battled and beat breast cancer in 1990 and moved to a retirement home ‘De Westerkim’ in May 1996, at the age of almost 106.

Also known as “Aunt Hennie” or “Grandma Hennie”, Van Andel-Schipper gained significant media coverage in her later years, as she was the oldest inhabitant of the Netherlands for a couple of years, met with members of the Dutch royal family at regular intervals, and was often asked for her secrets to longevity. On top of that, with Mrs. Van Andel-Schipper being a fond supporter of the football club Ajax, the club would recognize her support by having its members visit her for her 115th birthday. Some two months later, Hendrikje van Andel-Schipper would die peacefully in her sleep. She was thought to be the world’s oldest living person after the death of Ramona Trinidad Iglesias-Jordan on 29 May 2004 until her death. However, that title was posthumously withdrawn on 9 December 2005, when Maria Capovilla of Ecuador, born 14 September 1889, was recognized as the world’s oldest living person.

Well before she had lived to old age, she had agreed to donate her body to the University of Groningen at the age of 82 in 1972; the autopsy performed on her revealed that she had died of advanced stomach cancer that had gone undetected. However, later research revealed that it was probable that Mrs. Van Andel-Schipper would not have lived much longer, as she had only two blood stem cells left functioning; this led to the speculation that the human body is not able to live infinitely, as after a certain amount of time the body is not able anymore to produce new cells.

Another revelation from the autopsy was that Mrs. Van Andel-Schipper’s body seemed to age more slowly than the average one; her brain showed no sign of dementia and did not suffer from arteriosclerosis (one of the main causes of heart problems). On top of that, at the age of 113, Mrs. Van Andel-Schipper scored the average result of a 60- or 70-year-old in a memory test. All of this seemed to suggest that mutations in her body caused her to age slower than other people.

Following Mrs. Van Andel-Schipper’s example, Egbertje Leutscher-de Vries (another Dutch supercentenarian) also left her body to science; results of her autopsy further supported the hypothesis that genetic mutations (thus, a genetic cause) are at least partly the reason why supercentenarians grow older than other people.