Augusta Louise Holtz was born in Czarnikau, Prussian Province of Posen of the German Empire, now Czarnkow, Czarnkow-Trzcianka County, Greater Poland Voivodeship, Poland, on 3 August 1871. Her parents were Michael and Wilhemina Henrietta (Quade) Hoppe.

Holtz moved to the U.S. aged 2 in 1873. Her father owned a farm near Troy, Illinois. She grew up with three siblings. She married Edward Holtz in 1900, who died in 1923. She had four children with him – two sons (Edward and Augustus) and two daughters (Hester and Gertrude). She later moved to St. Louis County, Missouri, where she died at the St. Sophia Geriatric Center in Florissant.

Holtz maintained her cognitive faculties into her final years, retaining a good memory that allowed for her to list off the names of all 23 US presidents she had lived under. She also enjoyed keeping up on current events, which included public figures like Nancy Reagan and Princess Diana. When asked for her secret to longevity, she suggested to “keep having birthdays.”

By the time of her 114th birthday in 1985, she was confined to a hospital bed and suffered from failing eyesight and hearing. However, on her 115th birthday in 1986, she was described as being more perky and talkative than in the prior year. She told her daughters that she believed this would be her last birthday, and that she felt ready to die.